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Real-time fluorescence assays to monitor duplex unwinding and ATPase activities of helicase proteins

Many physiological functions of helicases are dependent on their ability to unwind nucleic acid duplexes in an ATP-dependent fashion. Determining the kinetic frameworks of these processes is critical to understand how these proteins function. We recently developed a fluorescence assay to monitor RNA...

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Détails bibliographiques
Publié dans:Nat Protoc
Auteurs principaux: Özeş, Ali R., Feoktistova, Kateryna, Avanzino, Brian C., Baldwin, Enoch P., Fraser, Christopher S.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524973/
https://ncbi.nlm.nih.gov/pubmed/24945382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2014.112
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