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Real-time fluorescence assays to monitor duplex unwinding and ATPase activities of helicase proteins

Many physiological functions of helicases are dependent on their ability to unwind nucleic acid duplexes in an ATP-dependent fashion. Determining the kinetic frameworks of these processes is critical to understand how these proteins function. We recently developed a fluorescence assay to monitor RNA...

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Dettagli Bibliografici
Pubblicato in:Nat Protoc
Autori principali: Özeş, Ali R., Feoktistova, Kateryna, Avanzino, Brian C., Baldwin, Enoch P., Fraser, Christopher S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524973/
https://ncbi.nlm.nih.gov/pubmed/24945382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2014.112
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