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Real-time fluorescence assays to monitor duplex unwinding and ATPase activities of helicase proteins

Many physiological functions of helicases are dependent on their ability to unwind nucleic acid duplexes in an ATP-dependent fashion. Determining the kinetic frameworks of these processes is critical to understand how these proteins function. We recently developed a fluorescence assay to monitor RNA...

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Detalhes bibliográficos
Publicado no:Nat Protoc
Main Authors: Özeş, Ali R., Feoktistova, Kateryna, Avanzino, Brian C., Baldwin, Enoch P., Fraser, Christopher S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524973/
https://ncbi.nlm.nih.gov/pubmed/24945382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2014.112
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