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Duplex unwinding and ATPase activities of the DEAD-box helicase eIF4A are coupled by eIF4G and eIF4B

Eukaryotic initiation factor 4A (eIF4A) is a DEAD-box helicase that stimulates translation initiation by unwinding mRNA secondary structure. The accessory proteins, eIF4G, eIF4B, and eIF4H enhance the duplex unwinding activity of eIF4A, but the extent to which they modulate eIF4A activity is poorly...

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Bibliografski detalji
Glavni autori: Özeş, Ali R., Feoktistova, Kateryna, Avanzino, Brian C., Fraser, Christopher S.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3175293/
https://ncbi.nlm.nih.gov/pubmed/21840318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.08.004
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