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The eukaryotic initiation factor eIF4H facilitates loop-binding, repetitive RNA unwinding by the eIF4A DEAD-box helicase
Eukaryotic translation initiation is a highly regulated process in protein synthesis. The principal translation initiation factor eIF4AI displays helicase activity, unwinding secondary structures in the mRNAs 5′-UTR. Single molecule fluorescence resonance energy transfer (sm-FRET) is applied here to...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3401463/ https://ncbi.nlm.nih.gov/pubmed/22457067 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks278 |
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