Selective Modification of Eukaryotic Initiation Factor 4F (eIF4F) at the Onset of Cell Differentiation: Recruitment of eIF4GII and Long-Lasting Phosphorylation of eIF4E

mRNA translation is mainly regulated at the level of initiation, a process that involves the synergistic action of the 5′ cap structure and the 3′ poly(A) tail at the ends of eukaryotic mRNA. The eukaryote initiation factor 4G(eIF4G) is a pivotal scaffold protein that forms a critical link between m...

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Autores principales: Caron, Sandrine, Charon, Martine, Cramer, Elisabeth, Sonenberg, Nahum, Dusanter-Fourt, Isabelle
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2004
Materias:
Gene Expression
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC416417/
https://ncbi.nlm.nih.gov/pubmed/15143184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.11.4920-4928.2004
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