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Factor-dependent processivity in human eIF4A DEAD-box helicase
During eukaryotic translation initiation, the small ribosomal subunit, assisted by initiation factors, locates the messenger RNA start codon by scanning from the 5′ cap. This process is powered by the eukaryotic initiation factor 4A (eIF4A), a DEAD-box helicase. eIF4A has been thought to unwind stru...
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| Veröffentlicht in: | Science |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4605566/ https://ncbi.nlm.nih.gov/pubmed/26113725 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaa5089 |
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