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Real-time fluorescence assays to monitor duplex unwinding and ATPase activities of helicase proteins

Many physiological functions of helicases are dependent on their ability to unwind nucleic acid duplexes in an ATP-dependent fashion. Determining the kinetic frameworks of these processes is critical to understand how these proteins function. We recently developed a fluorescence assay to monitor RNA...

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書目詳細資料
發表在:Nat Protoc
Main Authors: Özeş, Ali R., Feoktistova, Kateryna, Avanzino, Brian C., Baldwin, Enoch P., Fraser, Christopher S.
格式: Artigo
語言:Inglês
出版: 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524973/
https://ncbi.nlm.nih.gov/pubmed/24945382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2014.112
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