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A cell-based, quantitative and isoform-specific assay for exchange proteins directly activated by cAMP

Extensive functional studies of the exchange protein directly activated by cAMP (EPAC) family of signaling molecules have demonstrated that EPAC proteins play a fundamental role in several physiological and pathophysiological responses, therefore are attractive drug targets. In this report, the deve...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Zhu, Yingmin, Mei, Fang, Luo, Pei, Cheng, Xiaodong
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524698/
https://ncbi.nlm.nih.gov/pubmed/28740152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06432-4
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