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A cell-based, quantitative and isoform-specific assay for exchange proteins directly activated by cAMP

Extensive functional studies of the exchange protein directly activated by cAMP (EPAC) family of signaling molecules have demonstrated that EPAC proteins play a fundamental role in several physiological and pathophysiological responses, therefore are attractive drug targets. In this report, the deve...

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Pubblicato in:Sci Rep
Autori principali: Zhu, Yingmin, Mei, Fang, Luo, Pei, Cheng, Xiaodong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524698/
https://ncbi.nlm.nih.gov/pubmed/28740152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06432-4
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