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A cell-based, quantitative and isoform-specific assay for exchange proteins directly activated by cAMP

Extensive functional studies of the exchange protein directly activated by cAMP (EPAC) family of signaling molecules have demonstrated that EPAC proteins play a fundamental role in several physiological and pathophysiological responses, therefore are attractive drug targets. In this report, the deve...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhu, Yingmin, Mei, Fang, Luo, Pei, Cheng, Xiaodong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524698/
https://ncbi.nlm.nih.gov/pubmed/28740152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06432-4
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