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Isoform-specific antagonists of exchange proteins directly activated by cAMP

The major physiological effects of cAMP in mammalian cells are transduced by two ubiquitously expressed intracellular cAMP receptors, protein kinase A (PKA) and exchange protein directly activated by cAMP (EPAC), as well as cyclic nucleotide-gated ion channels in certain tissues. Although a large nu...

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Detalhes bibliográficos
Main Authors: Tsalkova, Tamara, Mei, Fang C., Li, Sheng, Chepurny, Oleg G., Leech, Colin A., Liu, Tong, Holz, George G., Woods, Virgil L., Cheng, Xiaodong
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494926/
https://ncbi.nlm.nih.gov/pubmed/23091014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1210209109
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