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“A-kinase” regulator runs amok to provide a paradigm shift in cAMP signaling

The activity of the archetypal protein kinase A (PKA) is typically thought of in regards to the catalytic subunit, which is inhibited by the regulatory subunits in the absence of cAMP. However, it is now reported that one of the regulatory subunit isoforms (PKA-RIα) takes on a function of its own up...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Holz, George G., Chepurny, Oleg G., Leech, Colin A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6378975/
https://ncbi.nlm.nih.gov/pubmed/30765510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.H119.007622
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