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Expression of cAMP-Regulated Guanine Nucleotide Exchange Factors in Pancreatic β-Cells
The insulinotropic hormone glucagon-like peptide-1 (GLP-1) binds to a Gs-coupled receptor on pancreatic β-cells and potentiates glucose-induced insulin secretion, insulin gene transcription, and β-cell growth. These stimulatory effects have been attributed to the elevation of intracellular cAMP leve...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2000
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2924611/ https://ncbi.nlm.nih.gov/pubmed/11071853 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1006/bbrc.2000.3763 |
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