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Expression of cAMP-Regulated Guanine Nucleotide Exchange Factors in Pancreatic β-Cells
The insulinotropic hormone glucagon-like peptide-1 (GLP-1) binds to a Gs-coupled receptor on pancreatic β-cells and potentiates glucose-induced insulin secretion, insulin gene transcription, and β-cell growth. These stimulatory effects have been attributed to the elevation of intracellular cAMP leve...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2000
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2924611/ https://ncbi.nlm.nih.gov/pubmed/11071853 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1006/bbrc.2000.3763 |
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