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cAMP-regulated guanine nucleotide exchange factor II (Epac2) mediates Ca(2+)-induced Ca(2+) release in INS-1 pancreatic β-cells
1. The signal transduction pathway responsible for cAMP-dependent Ca(2+)-induced Ca(2+) release (CICR) from endoplasmic reticulum Ca(2+) stores was assessed in the insulin-secreting cell line INS-1. 2. CICR was triggered by the GLP-1 receptor agonist exendin-4, an effect mimicked by caffeine, Sp-cAM...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Blackwell Science Inc
2001
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2278885/ https://ncbi.nlm.nih.gov/pubmed/11600673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.2001.0375c.xd |
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