Site-specific cleavage of RNA by Fe(II).bleomycin.
Bleomycin is an antitumor agent whose activity has long been thought to derive from its ability to degrade DNA. Recent findings suggest that cellular RNA may be a therapeutically relevant locus. At micromolar concentrations, Fe(II)-bleomycin readily cleaved a Bacillus subtilis tRNAHis precursor in a...
I tiakina i:
| I whakaputaina i: | Proc Natl Acad Sci U S A |
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| Ngā kaituhi matua: | , , , , , |
| Hōputu: | Artigo |
| Reo: | Inglês |
| I whakaputaina: |
National Academy of Sciences
1990
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| Ngā marau: | |
| Urunga tuihono: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55167/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1701259/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.23.9373 |
| Ngā Tūtohu: |
Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!
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