Wird geladen...

Site-specific cleavage of RNA by Fe(II).bleomycin.

Bleomycin is an antitumor agent whose activity has long been thought to derive from its ability to degrade DNA. Recent findings suggest that cellular RNA may be a therapeutically relevant locus. At micromolar concentrations, Fe(II)-bleomycin readily cleaved a Bacillus subtilis tRNAHis precursor in a...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Carter, B J, de Vroom, E, Long, E C, van der Marel, G A, van Boom, J H, Hecht, S M
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1990
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC55167/
https://ncbi.nlm.nih.gov/pubmed/1701259
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!