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Site-specific cleavage of RNA by Fe(II).bleomycin.

Bleomycin is an antitumor agent whose activity has long been thought to derive from its ability to degrade DNA. Recent findings suggest that cellular RNA may be a therapeutically relevant locus. At micromolar concentrations, Fe(II)-bleomycin readily cleaved a Bacillus subtilis tRNAHis precursor in a...

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Gorde:
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Carter, B J, de Vroom, E, Long, E C, van der Marel, G A, van Boom, J H, Hecht, S M
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 1990
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55167/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1701259/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.23.9373
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