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Cleavage of Simian Virus 40 DNA at a Unique Site by a Bacterial Restriction Enzyme

The R(1) restriction endonuclease of Escherichia coli converts covalently-closed circular Simian Virus 40 (SV40) DNA to unit-length linear duplex molecules. Cleavage occurs at a unique site, since denaturation and renaturation of these linear molecules yield linear but no circular molecules. The dis...

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Bibliographic Details
Main Authors: Morrow, John F., Berg, Paul
Format: Artigo
Language:Inglês
Published: 1972
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC389772/
https://ncbi.nlm.nih.gov/pubmed/4343967
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