On the Origin of Reverse Transcriptase-Using CRISPR-Cas Systems and Their Hyperdiverse, Enigmatic Spacer Repertoires

Cas1 integrase is the key enzyme of the clustered regularly interspaced short palindromic repeat (CRISPR)-Cas adaptation module that mediates acquisition of spacers derived from foreign DNA by CRISPR arrays. In diverse bacteria, the cas1 gene is fused (or adjacent) to a gene encoding a reverse trans...

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Библиографические подробности
Опубликовано в: :mBio
Главные авторы: Silas, Sukrit, Makarova, Kira S., Shmakov, Sergey, Páez-Espino, David, Mohr, Georg, Liu, Yi, Davison, Michelle, Roux, Simon, Krishnamurthy, Siddharth R., Fu, Becky Xu Hua, Hansen, Loren L., Wang, David, Sullivan, Matthew B., Millard, Andrew, Clokie, Martha R., Bhaya, Devaki, Lambowitz, Alan M., Kyrpides, Nikos C., Koonin, Eugene V., Fire, Andrew Z.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2017
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5513706/
https://ncbi.nlm.nih.gov/pubmed/28698278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00897-17
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