Simple Tetrahydroisoquinolines Are Potent and Selective Kappa Opioid Receptor Antagonists

Gelijkaardige items

• Potent and Selective Tetrahydroisoquinoline Kappa Opioid Receptor Antagonists of Lead Compound (3R)-N-[1R)-1-(Cyclohexylmethyl)-2-methylpropyl]-7-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxamide (CDTic)
  door: Kormos, Chad M., et al.
  Gepubliceerd in: (2018)
• Potent and Selective Tetrahydroisoquinoline Kappa Opioid Receptor Antagonists of Lead Compound (3R)‑7-Hydroxy‑N‑[(1S)‑2-methyl-1-(piperidin-1-ylmethyl)propyl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide (PDTic)
  door: Ondachi, Pauline W., et al.
  Gepubliceerd in: (2018)
• Discovery of N-{4-[(3-Hydroxyphenyl)-3-methylpiperazin-1-yl]methyl-2-methylpropyl}-4-phenoxybenzamide Analogues as Selective Kappa Opioid Receptor Antagonists
  door: Kormos, Chad M., et al.
  Gepubliceerd in: (2013)
• Design, Synthesis, and Biological Evaluation of Structurally Rigid Analogues of 4-(3-Hydroxyphenyl)piperidine Opioid Receptor Antagonists
  door: Runyon, Scott P., et al.
  Gepubliceerd in: (2016)
• 1-Substituted 4-(3-Hydroxyphenyl)piperazines Are Pure Opioid Receptor Antagonists
  door: Carroll, F. Ivy, et al.
  Gepubliceerd in: (2010)