Potent and Selective Tetrahydroisoquinoline Kappa Opioid Receptor Antagonists of Lead Compound (3R)-N-[1R)-1-(Cyclohexylmethyl)-2-methylpropyl]-7-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxamide (CDTic)

Gelijkaardige items

• Potent and Selective Tetrahydroisoquinoline Kappa Opioid Receptor Antagonists of Lead Compound (3R)‑7-Hydroxy‑N‑[(1S)‑2-methyl-1-(piperidin-1-ylmethyl)propyl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide (PDTic)
  door: Ondachi, Pauline W., et al.
  Gepubliceerd in: (2018)
• Design, Synthesis, and Biological Evaluation of (3R)-1,2,3,4-Tetrahydro-7-hydroxy-N-[(1S)-1-[[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl]-2-methylpropyl]-3-isoquinolinecarboxamide (JDTic) Analogues: In Vitro Pharmacology and ADME Profile
  door: Kormos, Chad M., et al.
  Gepubliceerd in: (2014)
• Analogues of (3R)-7-Hydroxy-N-[(1S)-1-{[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl}-2-methylpropyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide (JDTic). Synthesis and In Vitro and In Vivo Opioid Receptor Antagonist Activity
  door: Runyon, Scott P., et al.
  Gepubliceerd in: (2010)
• (S)-N-Benzyl-2-methyl-1,2,3,4-tetra­hydro­isoquinoline-3-carboxamide
  door: Naicker, Tricia, et al.
  Gepubliceerd in: (2010)
• Simple Tetrahydroisoquinolines Are Potent and Selective Kappa Opioid Receptor Antagonists
  door: Kormos, Chad M., et al.
  Gepubliceerd in: (2017)