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1-Substituted 4-(3-Hydroxyphenyl)piperazines Are Pure Opioid Receptor Antagonists
[Image: see text] This report describes the discovery that 1-substituted 4-(3-hydroxyphenyl)piperazines are pure opioid receptor antagonists. Compounds in this new series include N-phenylpropyl (3S)-3-methyl-4-(3-hydroxyphenyl)piperazine and (3R)-3-methyl-4-(3-hydroxyphenyl)piperazine, both of which...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Chemical Society
2010
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| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2992360/ https://ncbi.nlm.nih.gov/pubmed/21116435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml100126b |
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