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Transition State Structure of RNA Depurination by Saporin L3
Saporin L3 from the leaves of the common soapwort is a catalyst for hydrolytic depurination of adenine from RNA. Saporin L3 is a type 1 ribosome inactivating protein (RIP) composed only of a catalytic domain. Other RIPs have been used in immunotoxin cancer therapy, but off-target effects have limite...
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| Published in: | ACS Chem Biol |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5502533/ https://ncbi.nlm.nih.gov/pubmed/26886255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.5b01069 |
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