Calcineurin/NFAT Signaling in Activated Astrocytes Drives Network Hyperexcitability in Aβ-Bearing Mice

Hyperexcitable neuronal networks are mechanistically linked to the pathologic and clinical features of Alzheimer's disease (AD). Astrocytes are a primary defense against hyperexcitability, but their functional phenotype during AD is poorly understood. Here, we found that activated astrocytes in...

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Foilsithe in:J Neurosci
Main Authors: Sompol, Pradoldej, Furman, Jennifer L., Pleiss, Melanie M., Kraner, Susan D., Artiushin, Irina A., Batten, Seth R., Quintero, Jorge E., Simmerman, Linda A., Beckett, Tina L., Lovell, Mark A., Murphy, M. Paul, Gerhardt, Greg A., Norris, Christopher M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Society for Neuroscience 2017
Ábhair:
Research Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5481945/
https://ncbi.nlm.nih.gov/pubmed/28559377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0877-17.2017
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