Interleukin-1β-dependent Signaling between Astrocytes and Neurons Depends Critically on Astrocytic Calcineurin/NFAT Activity

Interleukin-1β (IL-1β) and the Ca(2+)/calmodulin-dependent protein phosphatase, calcineurin, have each been shown to play an important role in neuroinflammation. However, whether these signaling molecules interact to coordinate immune/inflammatory processes and neurodegeneration has not been investi...

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Detalhes bibliográficos
Main Authors: Sama, Michelle A., Mathis, Diana M., Furman, Jennifer L., Abdul, Hafiz Mohmmad, Artiushin, Irina A., Kraner, Susan D., Norris, Christopher M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Mechanisms of Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2494911/
https://ncbi.nlm.nih.gov/pubmed/18541537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800148200
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