Cognitive Decline in Alzheimer's Disease Is Associated with Selective Changes in Calcineurin/NFAT Signaling

Upon activation by calcineurin, the nuclear factor of activated T-cells (NFAT) translocates to the nucleus and guides the transcription of numerous molecules involved in inflammation and Ca(2+) dysregulation, both of which are prominent features of Alzheimer's disease (AD). However, NFAT signal...

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Detalhes bibliográficos
Main Authors: Abdul, Hafiz Mohmmad, Sama, Michelle A., Furman, Jennifer L., Mathis, Diana M., Beckett, Tina L., Weidner, Adam M., Patel, Ela S., Baig, Irfan, Murphy, M. Paul, LeVine, Harry, Kraner, Susan D., Norris, Christopher M.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2782445/
https://ncbi.nlm.nih.gov/pubmed/19828810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1064-09.2009
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