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Cognitive Decline in Alzheimer's Disease Is Associated with Selective Changes in Calcineurin/NFAT Signaling

Upon activation by calcineurin, the nuclear factor of activated T-cells (NFAT) translocates to the nucleus and guides the transcription of numerous molecules involved in inflammation and Ca(2+) dysregulation, both of which are prominent features of Alzheimer's disease (AD). However, NFAT signal...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Abdul, Hafiz Mohmmad, Sama, Michelle A., Furman, Jennifer L., Mathis, Diana M., Beckett, Tina L., Weidner, Adam M., Patel, Ela S., Baig, Irfan, Murphy, M. Paul, LeVine, Harry, Kraner, Susan D., Norris, Christopher M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society for Neuroscience 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2782445/
https://ncbi.nlm.nih.gov/pubmed/19828810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1064-09.2009
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