Astrocyte Activation and the Calcineurin/NFAT Pathway in Cerebrovascular Disease

Calcineurin (CN) is a Ca(2+)/calmodulin-dependent protein phosphatase with high abundance in nervous tissue. Though enriched in neurons, CN can become strongly induced in subsets of activated astrocytes under different pathological conditions where it interacts extensively with the nuclear factor of...

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Bibliographic Details
Published in:Front Aging Neurosci
Main Authors: Kraner, Susan D., Norris, Christopher M.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2018
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6160594/
https://ncbi.nlm.nih.gov/pubmed/30297999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2018.00287
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