Calcineurin/NFAT Signaling in Activated Astrocytes Drives Network Hyperexcitability in Aβ-Bearing Mice

Hyperexcitable neuronal networks are mechanistically linked to the pathologic and clinical features of Alzheimer's disease (AD). Astrocytes are a primary defense against hyperexcitability, but their functional phenotype during AD is poorly understood. Here, we found that activated astrocytes in...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Sompol, Pradoldej, Furman, Jennifer L., Pleiss, Melanie M., Kraner, Susan D., Artiushin, Irina A., Batten, Seth R., Quintero, Jorge E., Simmerman, Linda A., Beckett, Tina L., Lovell, Mark A., Murphy, M. Paul, Gerhardt, Greg A., Norris, Christopher M.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5481945/
https://ncbi.nlm.nih.gov/pubmed/28559377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0877-17.2017
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados