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Ca(2+), Astrocyte Activation and Calcineurin/NFAT Signaling in Age-Related Neurodegenerative Diseases

Mounting evidence supports a fundamental role for Ca(2+) dysregulation in astrocyte activation. Though the activated astrocyte phenotype is complex, cell-type targeting approaches have revealed a number of detrimental roles of activated astrocytes involving neuroinflammation, release of synaptotoxic...

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Detalhes bibliográficos
Publicado no:Front Aging Neurosci
Main Authors: Sompol, Pradoldej, Norris, Christopher M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6046440/
https://ncbi.nlm.nih.gov/pubmed/30038565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2018.00199
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