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Nucleophosmin (B23) Targets ARF to Nucleoli and Inhibits Its Function
The ARF tumor suppressor is a nucleolar protein that activates p53-dependent checkpoints by binding Mdm2, a p53 antagonist. Despite persuasive evidence that ARF can bind and inactivate Mdm2 in the nucleoplasm, the prevailing view is that ARF exerts its growth-inhibitory activities from within the nu...
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| 出版年: | Mol Cell Biol |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Taylor & Francis
2005
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC548001/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15684379/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.25.4.1258-1271.2005 |
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