Nucleophosmin (B23) Targets ARF to Nucleoli and Inhibits Its Function

The ARF tumor suppressor is a nucleolar protein that activates p53-dependent checkpoints by binding Mdm2, a p53 antagonist. Despite persuasive evidence that ARF can bind and inactivate Mdm2 in the nucleoplasm, the prevailing view is that ARF exerts its growth-inhibitory activities from within the nu...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Cell Biol
Egile Nagusiak: Korgaonkar, Chandrashekhar, Hagen, Jussara, Tompkins, Van, Frazier, April A., Allamargot, Chantal, Quelle, Frederick W., Quelle, Dawn E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 2005
Gaiak:
Signal Transduction
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC548001/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15684379/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.25.4.1258-1271.2005
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak