Φορτώνει......
Ligand-induced activation of human TRPM2 requires the terminal ribose of ADPR and involves Arg1433 and Tyr1349
TRPM2 (transient receptor potential channel, subfamily melastatin, member 2) is a Ca(2+)-permeable non-selective cation channel activated by the binding of adenosine 5′-diphosphoribose (ADPR) to its cytoplasmic NUDT9H domain (NUDT9 homology domain). Activation of TRPM2 by ADPR downstream of oxidativ...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Biochem J |
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| Κύριοι συγγραφείς: | , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Portland Press Ltd.
2017
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5473349/ https://ncbi.nlm.nih.gov/pubmed/28515263 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20170091 |
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