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Integrin α2β1 in nonactivated conformation can induce focal adhesion kinase signaling
Conformational activation of integrins is generally required for ligand binding and cellular signalling. However, we have previously reported that the nonactivated conformation of α2β1 integrin can also bind to large ligands, such as human echovirus 1. In this study, we show that the interaction bet...
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| 發表在: | Sci Rep |
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| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group UK
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5469853/ https://ncbi.nlm.nih.gov/pubmed/28611383 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03640-w |
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