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Focal Adhesion Kinase Modulates Cell Adhesion Strengthening via Integrin Activation

Focal adhesion kinase (FAK) is an essential nonreceptor tyrosine kinase regulating cell migration, adhesive signaling, and mechanosensing. Using FAK-null cells expressing FAK under an inducible promoter, we demonstrate that FAK regulates the time-dependent generation of adhesive forces. During the e...

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Detalhes bibliográficos
Main Authors: Michael, Kristin E., Dumbauld, David W., Burns, Kellie L., Hanks, Steven K., García, Andrés J.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2675629/
https://ncbi.nlm.nih.gov/pubmed/19297531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-01-0076
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