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Quantification of Focal Adhesion Kinase Activation Loop Phosphorylation as a Biomarker of Src Activity

A recently developed stable isotope dilution liquid chromatography-multiple reaction/mass spectrometry method to quantify focal adhesion kinase (FAK) activation loop phosphorylation was used to study endogenous Src kinase activity. This revealed that bis-phosphorylated pTyr(576)/Tyr(577)-FAK was a b...

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Detalhes bibliográficos
Main Authors: Ciccimaro, Eugene, Hanks, Steven K., Blair, Ian A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Pharmacology and Experimental Therapeutics 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2684915/
https://ncbi.nlm.nih.gov/pubmed/19098120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.108.052464
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