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Quantification of Focal Adhesion Kinase Activation Loop Phosphorylation as a Biomarker of Src Activity
A recently developed stable isotope dilution liquid chromatography-multiple reaction/mass spectrometry method to quantify focal adhesion kinase (FAK) activation loop phosphorylation was used to study endogenous Src kinase activity. This revealed that bis-phosphorylated pTyr(576)/Tyr(577)-FAK was a b...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Pharmacology and Experimental Therapeutics
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2684915/ https://ncbi.nlm.nih.gov/pubmed/19098120 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.108.052464 |
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