Src-Mediated Phosphorylation of Focal Adhesion Kinase Couples Actin and Adhesion Dynamics to Survival Signaling

Integrin-associated focal adhesions not only provide adhesive links between cellular actin and extracellular matrix but also are sites of signal transmission into the cell interior. Many cell responses signal through focal adhesion kinase (FAK), often by integrin-induced autophosphorylation of FAK o...

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Bibliographic Details
Main Authors: Westhoff, M. A., Serrels, B., Fincham, V. J., Frame, M. C., Carragher, N. O.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Cell Growth and Development
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC515031/
https://ncbi.nlm.nih.gov/pubmed/15340073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.18.8113-8133.2004
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