Pyk2- and Src-Dependent Tyrosine Phosphorylation of PDK1 Regulates Focal Adhesions

3-Phosphoinositide-dependent protein kinase 1 (PDK1) is a signal integrator that activates the AGC superfamily of serine/threonine kinases. PDK1 is phosphorylated on tyrosine by oxidants, although its regulation by agonists that stimulate G-protein-coupled receptor signaling pathways and the physiol...

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Detalhes bibliográficos
Main Authors: Taniyama, Yoshihiro, Weber, David S., Rocic, Petra, Hilenski, Lula, Akers, Marjorie L., Park, Jongsun, Hemmings, Brian A., Alexander, R. Wayne, Griendling, Kathy K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC262336/
https://ncbi.nlm.nih.gov/pubmed/14585963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.22.8019-8029.2003
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