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Absolute Quantification of Phosphorylation on the Kinase Activation Loop of Cellular Focal Adhesion Kinase by Stable Isotope Dilution Liquid Chromatography/Mass Spectrometry

A vital point of convergence for many signaling pathways at cellular focal adhesions is the interaction of two non-receptor tyrosine kinases, focal adhesion kinase (FAK) and Src. The binding of Src to FAK leads to the phosphorylation of Y(576) and Y(577), located within the activation loop domain of...

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Bibliografiske detaljer
Main Authors: Ciccimaro, Eugene, Hanks, Steven K., Blair, Ian A.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2706532/
https://ncbi.nlm.nih.gov/pubmed/19354260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac900204f
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