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Integrin-Linked Kinase: A Multi-functional Regulator Modulating Extracellular Pressure-Stimulated Cancer Cell Adhesion through Focal Adhesion Kinase and AKT

Cell adhesion is important in cancer metastasis. Malignant cells in cancer patients may be exposed to physical forces such as extracellular pressure and shear, that stimulate their adhesion to matrix proteins, endothelium and surgical wounds. Pressure induces phosphorylation of AKT and focal adhesio...

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Bibliografiske detaljer
Udgivet i:Cell Oncol
Main Authors: Wang, Shouye, Basson, Marc D.
Format: Artigo
Sprog:Inglês
Udgivet: IOS Press 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4619106/
https://ncbi.nlm.nih.gov/pubmed/19633364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/CLO-2009-0469
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