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Integrin-Linked Kinase: A Multi-functional Regulator Modulating Extracellular Pressure-Stimulated Cancer Cell Adhesion through Focal Adhesion Kinase and AKT

Cell adhesion is important in cancer metastasis. Malignant cells in cancer patients may be exposed to physical forces such as extracellular pressure and shear, that stimulate their adhesion to matrix proteins, endothelium and surgical wounds. Pressure induces phosphorylation of AKT and focal adhesio...

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Detalhes bibliográficos
Publicado no:Cell Oncol
Main Authors: Wang, Shouye, Basson, Marc D.
Formato: Artigo
Idioma:Inglês
Publicado em: IOS Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4619106/
https://ncbi.nlm.nih.gov/pubmed/19633364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/CLO-2009-0469
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