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Identification of functional domains in AKT responsible for distinct roles of AKT isoforms in pressure-stimulated cancer cell adhesion

Cell adhesion is a critical step in cancer metastasis, activated by extracellular forces such as pressure and shear. Reducing AKT1, but not AKT2, ablates the increase in cancer cell adhesion associated with 15 mmHg increased extracellular pressure. To identify the determinants of this AKT isoform sp...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Wang, Shouye, Basson, Marc D.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2007
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2180395/
https://ncbi.nlm.nih.gov/pubmed/17825284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2007.08.005
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