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Isoform-specific modulation of pressure-stimulated cancer cell proliferation and adhesion by alpha-actinin

INTRODUCTION: Intratumoral pressure may stimulate cancer proliferation while intravascular pressure promotes metastatic adhesion. α-actinin proteins facilitate focal adhesion formation and link focal adhesion complexes to the cytoskeleton. We hypothesized that α-actinin is the mechanotransducer that...

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Detalhes bibliográficos
Main Authors: Downey, Christina, Craig, David H., Basson, Marc D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837569/
https://ncbi.nlm.nih.gov/pubmed/21906716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.amjsurg.2011.06.019
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