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Identification of functional domains in AKT responsible for distinct roles of AKT isoforms in pressure-stimulated cancer cell adhesion
Cell adhesion is a critical step in cancer metastasis, activated by extracellular forces such as pressure and shear. Reducing AKT1, but not AKT2, ablates the increase in cancer cell adhesion associated with 15 mmHg increased extracellular pressure. To identify the determinants of this AKT isoform sp...
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| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2007
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2180395/ https://ncbi.nlm.nih.gov/pubmed/17825284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2007.08.005 |
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