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Integrin α2β1 in nonactivated conformation can induce focal adhesion kinase signaling
Conformational activation of integrins is generally required for ligand binding and cellular signalling. However, we have previously reported that the nonactivated conformation of α2β1 integrin can also bind to large ligands, such as human echovirus 1. In this study, we show that the interaction bet...
Uloženo v:
| Vydáno v: | Sci Rep |
|---|---|
| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group UK
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5469853/ https://ncbi.nlm.nih.gov/pubmed/28611383 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03640-w |
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