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Integrin-Specific Control of Focal Adhesion Kinase and RhoA Regulates Membrane Protrusion and Invasion

Cell invasion through extracellular matrix (ECM) is a hallmark of the metastatic cascade. Cancer cells require adhesion to surrounding tissues for efficient migration to occur, which is mediated through the integrin family of receptors. Alterations in expression levels of β1 and β3 integrins have pr...

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Detalhes bibliográficos
Main Authors: Costa, Patricia, Scales, Tim M. E., Ivaska, Johanna, Parsons, Maddy
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767638/
https://ncbi.nlm.nih.gov/pubmed/24040310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074659
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