Integrin-Specific Control of Focal Adhesion Kinase and RhoA Regulates Membrane Protrusion and Invasion

Cell invasion through extracellular matrix (ECM) is a hallmark of the metastatic cascade. Cancer cells require adhesion to surrounding tissues for efficient migration to occur, which is mediated through the integrin family of receptors. Alterations in expression levels of β1 and β3 integrins have pr...

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Bibliografiska uppgifter
Huvudupphovsmän: Costa, Patricia, Scales, Tim M. E., Ivaska, Johanna, Parsons, Maddy
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2013
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767638/
https://ncbi.nlm.nih.gov/pubmed/24040310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074659
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