RNF8 mediates histone H3 ubiquitylation and promotes glycolysis and tumorigenesis

Disassembly of nucleosomes in which genomic DNA is packaged with histone regulates gene expression. However, the mechanisms underlying nucleosome disassembly for gene expression remain elusive. We show here that epidermal growth factor receptor activation results in the binding of the RNF8 forkhead-...

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Dettagli Bibliografici
Pubblicato in:J Exp Med
Autori principali: Xia, Yan, Yang, Weiwei, Fa, Ming, Li, Xinjian, Wang, Yugang, Jiang, Yuhui, Zheng, Yanhua, Lee, Jong-Ho, Li, Jing, Lu, Zhimin
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2017
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5461008/
https://ncbi.nlm.nih.gov/pubmed/28507061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20170015
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