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USP11 Is a Negative Regulator to γH2AX Ubiquitylation by RNF8/RNF168
Ubiquitin modification at double strand breaks (DSB) sites is an essential regulator of signaling and repair. γH2AX extends from DSB sites and provides a platform for subsequent recruitment and amplification of DNA repair proteins and signaling factors. Here, we found that RNF8/RNF168 ubiquitylates...
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| I publikationen: | J Biol Chem |
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| Huvudupphovsmän: | , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Society for Biochemistry and Molecular Biology
2016
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4705413/ https://ncbi.nlm.nih.gov/pubmed/26507658 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.624478 |
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