Llwytho...
PKM2 Phosphorylates Histone H3 and Promotes Gene Transcription and Tumorigenesis
Tumor-specific pyruvate kinase M2 (PKM2) is essential for the Warburg effect. Besides its well-established role in aerobic glycolysis, PKM2 directly regulates gene transcription. However, the mechanism underlying this nonmetabolic function of PKM2 remains elusive. We show here that PKM2 directly bin...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , , , , , , , |
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| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2012
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3431020/ https://ncbi.nlm.nih.gov/pubmed/22901803 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.07.018 |
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